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Top 20 Nuclear Energy startups in USA
Oct 04, 2025 | By Alexander Gillet | 22 |
1
Funding: $94.9M
Zeno is developing next-generation radioisotope power systems that generate carbon-free, resilient power for decades.
Zeno is developing next-generation radioisotope power systems that generate carbon-free, resilient power for decades.
2
Funding: $1.4B
TerraPower focuses on developing a sustainable and economic nuclear energy system while reducing proliferation risks.
TerraPower focuses on developing a sustainable and economic nuclear energy system while reducing proliferation risks.
4
Funding: $900M
Pacific Fusion focuses on renewable energy generation, emphasizing affordable fusion power inspired by nature.
Pacific Fusion focuses on renewable energy generation, emphasizing affordable fusion power inspired by nature.
5
Funding: $629M
Kairos Power develops an advanced reactor technology that leverages TRI-Structural ISOtropic (TRISO) fuel in pebble form in combination with a low-pressure fluoride salt coolant.
Kairos Power develops an advanced reactor technology that leverages TRI-Structural ISOtropic (TRISO) fuel in pebble form in combination with a low-pressure fluoride salt coolant.
6
Funding: $469.6M
NuScale Power has developed a small modular reactor (SMR) to supply energy for electrical generation and other heat process applications.
NuScale Power has developed a small modular reactor (SMR) to supply energy for electrical generation and other heat process applications.
7
Funding: $440M
Oklo is building an always on, container-sized, truly carbon-free and emission-free nuclear generator.
Oklo is building an always on, container-sized, truly carbon-free and emission-free nuclear generator.
8
Funding: $218.8M
Radiant develops portable nuclear microreactors as clean energy alternatives.
Radiant develops portable nuclear microreactors as clean energy alternatives.
9
Funding: $218.8M
Radiant develops portable nuclear microreactors for US military bases as clean energy alternatives.
Radiant develops portable nuclear microreactors for US military bases as clean energy alternatives.
10
Funding: $136M
Aalo makes small, factory-manufactured nuclear reactors that can fit in your garage, and power anything from a datacenter to a large city.
Aalo makes small, factory-manufactured nuclear reactors that can fit in your garage, and power anything from a datacenter to a large city.
11
Funding: $64M
Last Energy is creating a new system for the development and delivery of small modular nuclear power plants.
Last Energy is creating a new system for the development and delivery of small modular nuclear power plants.
12
Funding: $51M
The Nuclear Company is a fleet-scale nuclear development company using proven technology to construct a series of nuclear power plants across America.
The Nuclear Company is a fleet-scale nuclear development company using proven technology to construct a series of nuclear power plants across America.
13
Funding: $45M
Blue Energy is a nuclear power plant company that provides reliable, clean, and abundant electricity.
Blue Energy is a nuclear power plant company that provides reliable, clean, and abundant electricity.
14
Funding: $26.6M
Phoenix designs and manufactures the highest-yielding neutron generators and commercializes nuclear technologies for practical applications.
Phoenix designs and manufactures the highest-yielding neutron generators and commercializes nuclear technologies for practical applications.
15
Funding: $18.1M
Clean Core Thorium Energy develops advanced nuclear fuel for existing reactors.
Clean Core Thorium Energy develops advanced nuclear fuel for existing reactors.
16
Funding: $13M
Nuclearn is a software company delivering AI solutions for automating Nuclear Industry tasks.
Nuclearn is a software company delivering AI solutions for automating Nuclear Industry tasks.
17
Funding: $6.9M
Blue Wave AI Labs is using predictive analytics to operate nuclear reactors across the United States and to help them operate as safely and efficiently as possible
Blue Wave AI Labs is using predictive analytics to operate nuclear reactors across the United States and to help them operate as safely and efficiently as possible
18
Funding: $5.5M
Transatomic Power is a nuclear reactor design company offering a waste-annihilating molten salt reactor.
Transatomic Power is a nuclear reactor design company offering a waste-annihilating molten salt reactor.
19
Funding: $4M
Deep Fission is transforming the energy landscape by installing modular nuclear power reactors a mile deep.
Deep Fission is transforming the energy landscape by installing modular nuclear power reactors a mile deep.
20
Funding: $150K
Atomic Alchemy is to become the world’s most reliable supplier of radioisotopes for medical, research, exploration, and industrial use
Atomic Alchemy is to become the world’s most reliable supplier of radioisotopes for medical, research, exploration, and industrial use
